A PDF file is an Adobe file that stands for Portable Digital File. It captures formatting information and can be used without using your application software. It can be opened with Adobe Acrobat, or any version of Adobe Reader and is viewable and printable on virtually any platform.
Make sure to embed your fonts when creating your PDF.
The bleed measurement when added to the trim size measurement will equal the final size of the PDFs that are required for successful upload and printing.